Poster Session 2 — ASN Events

Poster Session 2 — ASN Events

Poster Session 2

Integrated Single-Cell Chromatin Accessibility and Gene Expression Profiling Reveals Regulatory Programs in Acute Myeloid Leukemia (#201)

Reza Mr Ghamsari

Challenges in developing a novel screen to identify 3D genome architecture regulators (#202)

Capturing genome-wide dynamics of bivalent chromatin in breast cancer (#203)

Vascular endothelial growth factor signalling is a gatekeeper of haematopoietic stem cell development (#204)

Alexander Maytum

A novel biosensor to identify regulators of individual and combinatorial histone modifications in live single cells (#205)

Exploring an epigenetic approach towards treatment for the genomic imprinting disorder Prader-Willi Syndrome (#206)

Megan Iminitoff

INTS6 and INTS6L not your common paralogues (#207)

Understanding the delivery of an ASO therapy for epidermolysis bullosa (#208)

Reconstructing pedigrees from identity-by-descent for disease gene discovery (#210)

Three-dimensional genome architectural and regulatory network changes define blood stem cell ageing (#211)

Quinn Stacpoole

TNT reprogramming corrects X inactivation in human female induced pluripotent stem cells (#212)

Characterising the distribution and sequence composition of ZFHX3 GGC repeat expansions in ALS (#213)

Long-Read Single-Cell Transcriptomics Illuminates Isoform Programs in Brain Development (#214)

Sefi D.J Prawer

A single-cell multi-omic atlas of human primary immunodeficiencies identified cell type defects associated with poor vaccination responses (#215)

Davide Vespasiani

Chromatin remodelling activates endogenous retroviruses (ERVs) to trigger viral mimicry in CDK4/6 inhibitor resistant breast cancer (#216)

Defining Nannarin biosynthesis: Genomics in an endangered species (#217)

Arnab Singha Mahapatra

Elucidating RNA isoform expression in the 2-day old human prefrontal cortex at single-cell resolution (#218)

Marcus R Camilleri

On the origin of sex differences in gene regulation (#219)

Transient loss of the tumor suppressor crebbp reshapes T-cell fate and anti-cancer immune responses (#220)

Aleen Al Halawani

Biomarker and Therapeutic Potential of Circular RNAs in Ovarian Cancer (#221)

Sineth Wijekoon Mudiyanselage

Considering sex and sex differences in clinical research: a systematic review (#222)

Dynamic transcriptome-scale RNA-targeting with Cas13 (#223)

Exploratory framework for genotype-phenotype prediction (#224)

Muhammad Muneeb

Identification of Novel Candidate Variants in Disorders of Sex Development Using Whole-Genome Sequencing (#225)

Shirin Moradi Fard

Deciphering the genetic causes of autoimmunity: from non-coding GWAS variants to target genes (#226)

Viacheslav A. Kriachkov

Identification of de novo LTR retrotransposon insertions arising during mouse embryonic development (#228)

Alexander L Carleton

High-resolution mapping of chromatin architecture in human osteoclasts using Micro-C to link non-coding GWAS variants to gene regulation (#229)

Retrospective single cell lineage tracing with expressed somatic mitochondrial variants (#230)

Co-visualization of G-quadruplexes and i-Motifs in breast cancer cells (#231)

Hormone-Driven Muscle Adaptation in Transgender Individuals: A Multi-Omic Dissection from the GAME Study (#232)

Bernadette Jones-Freeman

MAP3K7 as a candidate gene for syndromic DSD: three new cases report with novel variants identified by whole exome sequencing (#233)

Ancestral and environmental diversity shape the adaptive immune landscape in Indonesia (#234)

Irene Gallego Romero

The BET family of histone code readers modulate CHD4 chromatin remodelling activity (#235)

Lucien Lambrechts

Enabling long-read single-cell proteogenomics with GenomeProtSC (#236)

Molecular profiling of Tasmanian Devil facial tumour vulnerabilities using whole genome CRISPR screening (#237)

Removing contamination from image-based spatial transcriptomics data with DenoIST (#238)

Davis J McCarthy

Identifying novel targets for intervention through multi-omics studies in brain tissues of individuals with Prader-Willi syndrome (#239)

Shokouh Shahrokhi

Decoding Fibroblast Plasticity in Skin Regeneration and Fibrosis (#240)

Investigating the causality of genetic variants driving splicing changes using CRISPR-Cas9 base-editing (#241)

Michael Gitonobel

Decoding genome awakening during seed germination using single-cell analysis, multiomics and spatial transcriptomics (#242)

Mathew G Lewsey

Experimental analysis of the genomic determinants of tissue-specific splicing (#243)

How do chromatin readers modulate the activity of chromatin remodellers? (#244)

Clement CL Luong

Beyond the Paradigm: When Foundations Aren’t Enough for Spatial and Single-Cell Omics (#245)

Hamid Alinejad Rokny

Exploring the Efficiency of Multi-Target Editing of Variants implicated in Bone Marrow Failure Syndromes with Single Base Editors (#246)

Kirsten Fairfax

Dissecting the roles of Nr6a1 at early stages of the mouse hindlimb development (#248)

Quantitative imaging of chromatin compaction versus access on a nanoscale in a living cell (#249)

Elizabeth Hinde

The molecular choreography of epigenetic enhancer remodelling in early human development (#250)

Adrienne E Sullivan

Point mutation in a histidine to glutamate catabolic enzyme modulates behavioural adaptation to environment (#251)

Andrew D Johnston

From bottleneck to pipeline: Robotic EM-seq processing for population-scale methylome profiling (#252)

Genome evolution of asexual reproduction in New Zealand stick insect hybrids (#253)

Molecular dissection of cellular response to deadly Irukandji venom (#254)

Matthew A Waller

TTN missense variant affecting a conserved Ig-domain residue as a cause of familial dilated cardiomyopathy (#255)

YuChen CC Chang

CRISPR-screen Links FBXW11 as a Regulator of Brain Organoid Size and Neuronal Maturation Programs. (#256)

Single molecule tracking of homologous histone methyltransferases SUV39H1 and SET-25 (#257)

Natalya Frolows

Identifying human cell factors mediating potato toxicity (#258)

Mathew MS Samuel

More than a C. elegans methyltransferase: uncovering alternate pathways for H3K9me3 deposition in epigenetic inheritance (#259)

Viral structurome and epitranscriptome as therapeutic targets (#260)

Integrated CRISPR activation and knockout screens with single-cell profiling in CD4+ T cells (#261)

Maximilian Jordan

mRNArchitect: a toolkit for the design of mRNA sequences (#262)

Genomics Infrastructure to Support Australian Researchers (#263)

Capturing long-term hippocampal development in vitro using a novel stem cell-derived 3D brain organoid model system (#264)

Maria Giovanna Garone

Investigating the role of NSD1 in the pathogenesis of Sotos syndrome using brain organoids (#265)

Zbtb48: a role for telomere dynamics in long-term chronic pain. (#266)

Hannah Scarborough

DNA methylation reveals hidden cis-regulatory elements beyond chromatin accessibility during human development (#267)