Poster Session 1 — ASN Events

Poster Session 1 — ASN Events

Poster Session 1

Transcriptional repression of endogenous retroviral elements in human B cells (#101)

Development of antisense therapeutics for psoriasis (#102)

An Integrative Multiomics Approach to Characterise Novel Transcripts Underlying the Maintenance of Pluripotency and Cellular Differentiation (#103)

Epigenetic Rewiring of Epithelial Plasticity in Triple Negative Breast Cancer (TNBC) Reshapes the Immune Microenvironment. (#104)

Intrinsically disordered regions and their importance in SET-9 and SET-26 (#105)

Unravel the role of nucleic binding ability of the epigenetic regulator SMCHD1 (#106)

Stepping towards the silencing: how Ep400 regulates the timely onset of Xist and Xi establishment in female X chromosome inactivation (#107)

Visualising endogenous gene expression dynamics (#108)

Bailey BHM Hiles-Murison

KLF3 is required for normal CD8+ T cell development (#109)

MMBWAP: Macquarie university Motor neuron – Bioinformatics Whole genome Analysis Pipeline (#110)

Are your antibodies cheating on their binding partners? Screening antibody specificity in CUT&Tag (#111)

Leighton S Ditchburn

Development of a reproducible Nextflow pipeline for somatic variant detection in high-depth whole-genome sequencing of neurodegenerative disease (#112)

Daniel O'Shaughnessy

Genome-wide CRISPR-KO library screen reveals ribosome biogenesis as a genetic vulnerability in ARID1A-mutant ovarian clear cell carcinoma. (#113)

Discovery of a conserved program of shared neural-endocrine microexon splicing regulated by SRRM3/4 (#114)

Annelies Hardiman

Leveraging alphafold-multimer to investigate potential A20 protein conformational changes arising from protein-protein interactions (#115)

A genetic modifier screen supports dispersed signalling in thermal responses of plants. (#116)

Beyond weight loss – epigenetic memory and weight cycling after semaglutide treatment (#117)

A window into the past: looking at past chromatin states using EpiTracer (#118)

Subcellular proteomic networks underlying acute and chronic exercise responses in human skeletal muscle (#119)

Elizabeth Reisman

Characterising mitochondrial haplogroups and clinical features in Australian sporadic motor neuron disease (#120)

Quantification of bulk RNA modifications in yeast and human cells using mass spectrometry. (#121)

Pinpointing Schizophrenia Mechanisms with Isoform-Resolved Analyses in the Developing Human Brain (#122)

Mitchell Hodgson

Transcriptomic signatures and entropy dynamics of human ageing (#123)

Sex specific effects of ageing and exercise on androgen and estrogen receptor activity (#124)

Rushali Kulllachanda Aiyanna

Meta-analysis of substantia nigra transcriptomic sex differences in association with Parkinson’s disease (#125)

Shihan Mr Zhang

Assessing Kolmogorov-Arnold networks for single-cell gene expression analysis (#126)

Sandeep Santhosh Kumar

Investigating X-inactivation escape in immune cells of female lupus patients using long-read single-cell sequencing (#127)

H3K4me3 disruption in the C. elegans germline (#128)

Investigating variation in the protein-coding genome of a variable immune-deficient cohort (#129)

James Lancaster

Is Iron a novel regulator of SRY in Parkinson’s disease? (#130)

Malack Abuelbashar

Revealing Master Transcription Factor Networks Driving Neuroendocrine-like Reprogramming in Prostate Cancer (#131)

Tianjun TZ Zhang

Harnessing drug-induced epigenetic memory for rational and effective sequential therapy in cancer. (#132)

Benchmarking long-read fusion detection across tools and technologies (#133)

Functional genomics screening of human transcription factors reveals mechanisms of tumour immune evasion (#134)

Investigating the structural basis for the interaction between the chromatin remodeler CHD4 and the BET-bromodomain proteins. (#135)

Investigating the mechanism and function of unstable X chromosome inactivation in female-biased autoimmune disorders (#136)

Xist rna dynamics reveal flexible silencing in B cell maturation and implications for x-linked autoimmunity. (#137)

Karina KP Pazaky

Accurate detection of small non-coding RNAs using NEBNext® Low-bias Small RNA Library Prep Kit (#138)

Proline-adjacent Phosphosites on Saccharomyces cerevisiae Histone Demethylase Rph1p are Salt Stress Responsive and Important for Cell Growth Under Salt Stress (#139)

Nicola Karakatsanis

Benchmarking single-cell transcriptomes and immune repertoires across technologies (#140)

Mapping Transcription Factor Search Dynamics with Pair Correlation Microscopy (#141)

Julissa Sanchez-Velasquez

Dissecting the Mechanism of DNA Protection by the Tardigrade Dsup Protein in Mammalian Chromatin (#142)

Joaquin Hinojosa Soto

Systematic profiling of chromatin factor expression and dependency across normal and malignant cells (#143)

Epigenetic Regulation of Stress-adaptive Survival in AML. (#144)

Dhammini Ekanayake

Investigating transcript diversity as a driver of melanoma progression and metastasis using nanopore long-read RNA sequencing (#145)

Phased Epigenomes: Haplotype-Specific Regulation in Hybrid Mouse Immune Cells (#146)

Hannah D Coughlan

Revealing the role of circRNA in pulmonary hypertension (#147)

Benjamin L Atchison

Investigating the genotype dependence of viral infection and immune phenotypes using genetically diverse human cell libraries (#148)

Steven M Heaton

Exploring the genome of immune memory in four dimensions (#149)

Timothy Johanson

Dissecting the genetic consequences of non-coding autoimmune risk variants in primary B cells (#150)

Jeralyn Wen Hui Ching

Mass spectrometry-based sequencing approaches to detect DNA and RNA modifications (#151)

Speckled Protein 140 (SP140) binds non-methylated gene promoters via its SAND domain. (#152)

Gabrielle R White

Modelling DNA demethylation dynamics during B cell maturation (#153)

Investigating the heterogeneity of acute myeloid leukaemia response to different classes of therapy using lineage tracing. (#154)

Modelling Brpf1-associated neurodevelopmental disorders in mice and trialling treatments (#156)

Sophie TB Morgan

Embryonic stem cell factors DPPA2/4 facilitate poised chromatin states in non-small cell lung cancer (#157)

Janith Seneviratne

Dual fluorescence detection system for multi-functional analysis of 3’ UTRs (#158)

Kara Henry-Cocks

Comprehensive analysis of the epigenetic landscape in ageing CD8⁺ T cells (#159)

Minh Anh (Morgan) MB Bui

AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS neurons (#160)

FMRpolyG and CGG repeat RNA synergistically induce neuroinflammation and neurodegeneration in FXTAS model systems. (#161)

Investigating the regulatory roles of microRNA clusters in neuroblastoma development (#162)

Regina Belen P Callanta

Genome-wide CRISPRa screen identifies host factors that enhance mRNA-LNP efficacy (#163)

limpa powers quantitative pulldown proteomics analysis for cancer epigenetics (#164)

Differentiation of IPS cells into fibroblasts to validate gene targets for Dupuytren’s Contracture (#165)

Towards re-engineering development in vivo (#166)